Saturday 12 May 2012

Clomiphene


Pronunciation: KLOE-mih-feen
Generic Name: Clomiphene
Brand Name: Clomid and Serophene


Clomiphene is used for:

Treating female infertility and forcertain conditions as determined by your doctor.


Clomiphene is an ovulatory stimulant. It works by helping to produce more hormones that cause your ovaries to release 1 or more eggs.


Do NOT use Clomiphene if:


  • you are allergic to any ingredient in Clomiphene

  • you are pregnant

  • you have abnormal vaginal bleeding

  • you have ovarian cysts (small growths on the ovaries) or enlargement not due to polycystic ovarian syndrome

  • you have or have ever had blockage of blood vessels (blood clots) in the legs, lungs, or other parts of the body

  • you have liver problems, uncontrolled thyroid or adrenal gland problems, or a brain lesion (eg, pituitary gland tumor)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Clomiphene:


Some medical conditions may interact with Clomiphene. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are planning to become pregnant or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have depression, endometriosis, polycystic ovarian syndrome, or uterine fibroids

Some MEDICINES MAY INTERACT with Clomiphene. However, no specific interactions with Clomiphene are known at this time.


Ask your health care provider if Clomiphene may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Clomiphene:


Use Clomiphene as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Clomiphene by mouth with or without food.

  • Properly timed sexual intercourse is important for good results. Ovulation usually occurs 5 to 10 days after a dose of Clomiphene.

  • If pregnancy has not been successful after 3 courses of treatment, further treatment is not recommended. Long-term use of Clomiphene is not recommended.

  • If you miss a dose of Clomiphene, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Clomiphene.



Important safety information:


  • Clomiphene may cause dizziness, lightheadedness, or vision disturbances, including blurring, spots, and flashes. These effects may be worse if you take it with alcohol or certain medicines. Use Clomiphene with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Enlargement of the ovaries may happen during or shortly after taking Clomiphene. Call your health care provider if you experience any stomach or pelvic pain, weight gain, pain, or stomach enlargement or discomfort while taking Clomiphene.

  • Pregnancy with more than 1 fetus (eg, twins) is possible while you are taking Clomiphene. Be sure you have discussed the potential complications and hazards of multiple pregnancy.

  • Lab tests, including pregnancy tests, may be performed while you use Clomiphene. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Clomiphene with caution in the ELDERLY; they may be more sensitive to its effects.

  • Clomiphene should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Do not use Clomiphene if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Clomiphene is found in breast milk. Do not breast-feed while taking Clomiphene.


Possible side effects of Clomiphene:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Blurred vision or vision problems (spots or flashes); breast tenderness; dizziness; enlarged breasts; enlargement of the ovaries; flushing; headache; hot flashes; lightheadedness; mood change; nausea; pelvic pain or bloating; stomach pain; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)increased risk of cancer of the ovaries; over stimulation of the ovaries; spontaneous abortion.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Clomiphene side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; flushing; nausea; stomach pain; vomiting.


Proper storage of Clomiphene:

Store Clomiphene at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Clomiphene out of the reach of children and away from pets.


General information:


  • If you have any questions about Clomiphene, please talk with your doctor, pharmacist, or other health care provider.

  • Clomiphene is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Clomiphene. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Clomiphene resources


  • Clomiphene Side Effects (in more detail)
  • Clomiphene Use in Pregnancy & Breastfeeding
  • Drug Images
  • Clomiphene Support Group
  • 10 Reviews for Clomiphene - Add your own review/rating


  • Clomiphene Prescribing Information (FDA)

  • Clomid Consumer Overview

  • Clomid Prescribing Information (FDA)

  • Clomiphene Citrate Monograph (AHFS DI)

  • Serophene Prescribing Information (FDA)

  • clomiphene Advanced Consumer (Micromedex) - Includes Dosage Information



Compare Clomiphene with other medications


  • Female Infertility
  • Lactation Suppression
  • Oligospermia
  • Ovulation Induction

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